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Nahaufnahme von Wassertropfen

Fast and easy screening of FcRn binding and release - enabled  by our high throughput plate-based PAIA assay platform

FcRn Bria Uste.png

Replace tedious SPR and HPLC methods to screen your molecules for FcRn binding and ensure favorable pharmacokinetics

Our FcRn assay measures binding to FcRn at four distinct pH values, allowing to predict physiological behaviour.

pH 5.8
pH 6.4
pH 7.0
pH 7.4

The assay generates profiles of equilibrium binding for the various pH levels - independently and in different wells.

De-risking of the FcRn interaction - crucial for ensuring efficient cellular recycling and low clearance.

Easy profiling of Fc mutations in protein engineering.
 

 Easy-to-automate
Low sample consumption
75 min for 96 samples

Read our PEGS 2026 poster
 

FcRn Fc mutations.png

ORDERING INFORMATION

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Each kit contains one ready-to-use 384-well PAIAplate and one bottle of reagent solution which is sufficient for the whole assay protocol. One kit can cover 96 samples.

 

Reach out to an application specialist by email to info@paiabio.com

For pricing information and placing orders please email to order@paiabio.com

ARTICLE
PA-DEV-4FcRn

FcRn Binding Assay Kit

pH: 5.8, 6.4, 7.0, 7.4

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